LYN anticorps (AA 201-300) (FITC)

N° du produit ABIN681500

Détail du produit anti-LYN anticorps (FITC)

Antigène: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Épitope: AA 201-300

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LYN est conjugé à/à la FITC

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Specificité: This protein is known to be similar in amino acid sequence to HCK. Therefore, cross-reactivity with this homologous protein may be observed

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Lyn

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-LYN (FITC) (ABIN681500)

Iriyama, Yuan, Hatta, Takagi, Takei et al.: "Lyn, a tyrosine kinase closely linked to the differentiation status of primary acute myeloid leukemia blasts, associates with negative regulation of all-trans retinoic acid (ATRA) and ..." dans: Cancer cell international, Vol. 16, pp. 37, (2016) (PubMed).

Détails sur LYN

Antigène: LYN (V-Yes-1 Yamaguchi Sarcoma Viral Related Oncogene Homolog (LYN))

Autre désignation: Lyn (LYN Produits)

Synonymes: anticorps JTK8, anticorps p53Lyn, anticorps p56Lyn, anticorps lyn, anticorps LYN, anticorps AA407514, anticorps Hck-2, anticorps jtk8, anticorps lyn-A, anticorps CH73-38P6.3, anticorps zgc:92124, anticorps LYN proto-oncogene, Src family tyrosine kinase, anticorps v-yes-1 Yamaguchi sarcoma viral related oncogene homolog, anticorps tyrosine-protein kinase Lyn, anticorps LYN proto-oncogene, Src family tyrosine kinase L homeolog, anticorps LYN, anticorps lyn, anticorps Lyn, anticorps LOC100593961, anticorps lyn.L

Sujet:

Synonyms: JTK8, p53Lyn, p56Lyn, Tyrosine-protein kinase Lyn, Lck/Yes-related novel protein tyrosine kinase, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, LYN

Background: This gene encodes a tyrosine protein kinase, which maybe involved in the regulation of mast cell degranulation, and erythroid differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

ID gène: 4067

UniProt: P07948

Pathways: Fc-epsilon Receptor Signaling Pathway, Hormone Transport, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling, Integrin Complex, BCR Signaling