IFNA2 anticorps

N° du produit ABIN6937478

Détail du produit anti-IFNA2 anticorps

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA2 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Specificité: Recognizes a protein of 16-27 kDa, identified as human interferon-II) (IFN-(II). Its epitope maps between aa112-148 of IFN-II) (total aa172). This MAb is specific for IFN-(II) and does not cross-react with IFN-(I). The site recognized by this MAb is called site I and is responsible for the antiviral and anti-proliferative activities of IFN-(II). Epitopes of N27 and N39 MAbs are different and represent a good combination of antibodies to set up an ELISA assay for the quantitation of IFN-(II) after viral infections. The IFN- family consists of 24 or more genes or pseudo-genes. IFN-II) is one of the two distinct families (I and II) of human IFN-. The -interferon are mainly produced by lymphocytes, monocytes, macrophages, and cell lines such as Namalwa and KG1 following induction by viruses, nucleic acids, and glucocorticoid hormones. They are involved in virus resistance on target cells, inhibition of cell proliferation, induction of cytokines and regulation of expression of MHC class I antigens.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Purified recombinant human IFN-alpha2

Clone: N39

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order Ab without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Stimulated human peripheral blood mononuclear cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur IFNA2

Antigène: IFNA2 (Interferon, alpha 2 (IFNA2))

Autre désignation: IFNA2 (IFNA2 Produits)

Synonymes: anticorps IFN-alphaA, anticorps IFNA, anticorps IFNA2B, anticorps INFA2, anticorps Ifa2, anticorps IFNA2, anticorps interferon alpha 2, anticorps interferon, alpha 2, anticorps interferon-alpha-2, anticorps interferon alpha-2, anticorps IFNA2, anticorps Ifna2, anticorps ifna2, anticorps IFN-ALPHA2, anticorps LOC102142148

Sujet: Alpha 2a interferon, IFN alpha, IFN-alpha-2, IFNA, IFNA2, IFNA2B, Interferon alpha 2a, Interferon alpha 2b, Interferon alpha-2, Interferon alpha-A, LeIF2, LeIFA,Interferon alpha-2 (IFNA2)
Cellular localisation: Cytoplasmic & Extracellular (Secreted)

Poids moléculaire: 16-27kDa

ID gène: 3440, 211575

UniProt: P01563

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Hepatitis C