SEMA4D/CD100 anticorps

N° du produit ABIN6939081

Détail du produit anti-SEMA4D/CD100 anticorps

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SEMA4D/CD100 est non-conjugé

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificité: Recognizes a homodimeric protein comprised of 50 kDa subunits, identified as CD100 (Workshop VI, Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Réactivité croisée (Details): Human, Baboon. Does not react with Horse,

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate.

Immunogène: PHA stimulated human peripheral blood lymphocytes.

Clone: 133-1C6

Isotype: IgM

Information d'application

Indications d'application:

Positive Control: Daudi, Raji, HUT-78, Kg1a, U937 and human lymphocytes. Human tonsils and lymph nodes.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Date de péremption: 24 months

Détails sur SEMA4D/CD100

Antigène: SEMA4D/CD100 (SEMA4D) (Sema Domain, Immunoglobulin Domain (Ig), Transmembrane Domain (TM) and Short Cytoplasmic Domain, (Semaphorin) 4D (SEMA4D))

Autre désignation: SEMA4D (SEMA4D Produits)

Synonymes: anticorps C9orf164, anticorps CD100, anticorps M-sema-G, anticorps SEMAJ, anticorps coll-4, anticorps Semacl2, anticorps Semaj, anticorps Semcl2, anticorps COLL-4, anticorps semaphorin 4D, anticorps sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D, anticorps Sema4d, anticorps SEMA4D

Sujet: COLL4, Collapsin4, GR3, M sema G, MSEMA, SEMA4D, Semacl2, SemaH, SEMAJ, Semaphorin C like 2, Semaphorin H, Semaphorin J, Semaphorin-4D, Semcl2,CD100 (Semaphorin-4D)
Cellular localisation: Cell surface

Poids moléculaire: 50kDa (Monomer)

ID gène: 10507, 494406

UniProt: Q92854

Pathways: Regulation of Cell Size