DPP4 anticorps

N° du produit ABIN6935162

Détail du produit anti-DPP4 anticorps

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DPP4 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Specificité: Recognizes a glycoprotein of 110 kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this MAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Aucune reactivité croisée: Porc, Mouton

Purification: Purified by Protein A/G

Immunogène: Human T cell clone

Clone: 202-36

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: YT, HEP-G2 cells and lymphocytes. Lymph nodes and tonsils.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Frozen Only) (0.5-1.0 μg/mL for 30 minutes at RT) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur DPP4

Antigène: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Autre désignation: DPP4 (DPP4 Produits)

Synonymes: anticorps ADABP, anticorps ADCP2, anticorps CD26, anticorps DPPIV, anticorps TP103, anticorps MGC81966, anticorps MOP9.8, anticorps MOP9_8, anticorps DPP4, anticorps si:ch73-2d23.3, anticorps Cd26, anticorps Dpp-4, anticorps THAM, anticorps dipeptidyl peptidase 4, anticorps dipeptidyl-peptidase 4 S homeolog, anticorps prolyl oligopeptidase family protein, anticorps dipeptidyl-peptidase 4, anticorps dipeptidylpeptidase 4, anticorps DPP4, anticorps dpp4.S, anticorps AT5G24260, anticorps dpp4, anticorps Dpp4

Poids moléculaire: 110kDa

ID gène: 1803

UniProt: P27487

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity