PAX6 anticorps (N-Term)
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- Antigène Voir toutes PAX6 Anticorps
- PAX6 (Paired Box 6 (PAX6))
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Épitope
- AA 1-300, N-Term
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Reactivité
- Humain, Souris, Rat, Poulet
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp PAX6 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificité
- Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters' anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
- Purification
- Purified by Protein A/G
- Immunogène
- Recombinant fragment (N-terminus, aa 1-300) of human PAX6 protein
- Clone
- PAX6-498
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product PAX6 Anticorps primaire
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- Indications d'application
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Positive Control: Pancreas or Cerebellum.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-80 °C
- Stockage commentaire
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Date de péremption
- 24 months
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- Antigène
- PAX6 (Paired Box 6 (PAX6))
- Autre désignation
- PAX6 (PAX6 Produits)
- Synonymes
- anticorps pax6, anticorps an2, anticorps mgda, anticorps wagr, anticorps pax-6, anticorps pax6a, anticorps xpax6, anticorps XLPAX6, anticorps MGC52531, anticorps PAX-6, anticorps AN, anticorps AN2, anticorps D11S812E, anticorps MGDA, anticorps WAGR, anticorps Pax-6, anticorps pax6b, anticorps 1500038E17Rik, anticorps AEY11, anticorps Dey, anticorps Gsfaey11, anticorps Sey, anticorps PAXZF-A, anticorps Pax6.1, anticorps cb280, anticorps fc20e07, anticorps pax-a, anticorps pax[zf-a], anticorps paxzfa, anticorps wu:fc20e07, anticorps zfpax-6a, anticorps zfpax-6b, anticorps paired box 6, anticorps paired box 6 L homeolog, anticorps paired box 6 S homeolog, anticorps paired box 6a, anticorps PAX6, anticorps pax6, anticorps Pax6, anticorps pax6.L, anticorps pax6.S, anticorps pax6a
- Poids moléculaire
- 47kDa
- ID gène
- 5080
- UniProt
- P26367
- Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
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