Transferrin Receptor anticorps (AA 94-212)

N° du produit ABIN6940700

Détail du produit anti-Transferrin Receptor anticorps

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Épitope: AA 94-212

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Transferrin Receptor est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)

Specificité: It recognizes a ~90-95 kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190 kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Purification: Purified by Protein A/G

Immunogène: Recombinant extracellular fragment (around aa 94-212) of human TFRC protein (exact sequence is proprietary)

Clone: TFRC-1818

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Positive Control: Jurkat, HeLa, MCF-7 or K562 cells. Human placenta or Bone Marrow.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur Transferrin Receptor

Antigène: Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

Autre désignation: TFRC (TFRC Produits)

Synonymes: anticorps Trfr, anticorps LOC100219280, anticorps tfr, anticorps cd71, anticorps tfr1, anticorps trfr, anticorps CD71, anticorps T9, anticorps TFR, anticorps TFR1, anticorps TR, anticorps TRFR, anticorps p90, anticorps 2610028K12Rik, anticorps AI195355, anticorps AI426448, anticorps AU015758, anticorps E430033M20Rik, anticorps Mtvr-1, anticorps Mtvr1, anticorps transferrin receptor, anticorps TFRC, anticorps Tfrc, anticorps tfrc

Poids moléculaire: 85-95kDa (monomer), 190kDa (dimer)

ID gène: 7037

UniProt: P02786

Pathways: Transition Metal Ion Homeostasis