Recombinant BCL10 anticorps (AA 122-168)

N° du produit ABIN6940988

L’anticorps Lapin Monoclonal anti-BCL10 a été validé pour IHC, IF, FACS et StM. Il convient pour détecter BCL10 dans des échantillons de Humain.

Aperçu rapide pour Recombinant BCL10 anticorps (AA 122-168) (ABIN6940988)

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp BCL10 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)

Clone: BL10-2988R

Détail du produit anti-BCL10 anticorps

Épitope: AA 122-168

Purification: Purified by Protein A/G

Immunogène: Recombinant human BCL10 protein fragment (around aa122-168) (exact sequence is proprietary)

Isotype: IgG

Information d'application

Indications d'application:

Positive Control: K562, HepG2 cells. Lymphoma.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur BCL10

Antigène: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Autre désignation: BCL10

Sujet: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1,14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NF14) translocation, while 55 % of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.

Poids moléculaire: 33kDa

ID gène: 8915

UniProt: O95999

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins