MYL2 anticorps
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- Antigène Voir toutes MYL2 Anticorps
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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Reactivité
- Souris, Rat, Poisson zèbre (Danio rerio)
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MYL2 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Réactivité croisée
- Souris, Rat, Poisson zèbre (Danio rerio)
- Purification
- Purified by Protein A.
- Immunogène
- Human Myosin Light Chain 2 between 150-250 amino acids
- Clone
- 10B7
- Isotype
- IgG
- Top Product
- Discover our top product MYL2 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
- Autre désignation
- Myosin Light Chain 2 (MYL2 Produits)
- Synonymes
- anticorps CMH10, anticorps MLC2, anticorps 2410014J02Rik, anticorps MLC-2, anticorps Mlc2, anticorps MLC-2v, anticorps Mlc2v, anticorps Mylpc, anticorps Mlc-2, anticorps myl2, anticorps zgc:136848, anticorps XMLC2, anticorps cmh10, anticorps mlc2, anticorps G2, anticorps MLC-2A, anticorps MLC2V, anticorps myosin light chain 2, anticorps myosin light chain, phosphorylatable, fast skeletal muscle, anticorps myosin, light polypeptide 2, regulatory, cardiac, slow, anticorps myosin, light chain 2b, regulatory, cardiac, slow, anticorps myosin light chain 2 S homeolog, anticorps myosin, light chain 2, regulatory, cardiac, slow, anticorps MYL2, anticorps Mylpf, anticorps Myl2, anticorps myl2b, anticorps myl2.S
- Sujet
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Synonyms: Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, Cardiac myosin light chain 2, Myosin light chain 2, slow skeletal/ventricular muscle isoform, Ventricular myosin light chain 2, MLC-2, MLC-2v, MLC-2s/v, MYL2
Background: Contractile protein that plays a role in heart development and function (PubMed:10409661). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion, as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) (PubMed:22426213, PubMed:16908724, PubMed:10409661). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (PubMed:9422794).
- ID gène
- 17906
- UniProt
- P51667
- Pathways
- Myometrial Relaxation and Contraction
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