ARPC5 anticorps
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- Antigène Voir toutes ARPC5 Anticorps
- ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))
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Reactivité
- Humain, Rat, Souris
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Hôte
- Lapin
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ARPC5 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- Recombinant human p16 ARC around N-terminus
- Clone
- 8D8
- Isotype
- IgG
- Top Product
- Discover our top product ARPC5 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C for 12 months.
- Date de péremption
- 12 months
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- Antigène
- ARPC5 (Actin Related Protein 2/3 Complex, Subunit 5, 16kDa (ARPC5))
- Autre désignation
- p16 ARC (ARPC5 Produits)
- Synonymes
- anticorps arc16, anticorps p16-arc, anticorps ARPC5, anticorps APOBEC4, anticorps ARC16, anticorps dJ127C7.3, anticorps p16-Arc, anticorps MGC86407, anticorps 5830443F10Rik, anticorps arpc5, anticorps fb09c07, anticorps fb12b05, anticorps fc56c07, anticorps wu:fb09c07, anticorps wu:fb12b05, anticorps wu:fc56c07, anticorps actin related protein 2/3 complex subunit 5, anticorps actin related protein 2/3 complex subunit 5 L homeolog, anticorps actin related protein 2/3 complex, subunit 5, anticorps actin related protein 2/3 complex, subunit 5B, anticorps actin related protein 2/3 complex, subunit 5A, anticorps ARPC5, anticorps arpc5, anticorps arpc5.L, anticorps Arpc5, anticorps arpc5b, anticorps arpc5a
- Sujet
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Synonyms: Actin-related protein 2/3 complex subunit 5, Arp2/3 complex 16 kDa subunit, p16-ARC, ARPC5
Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
- ID gène
- 10092
- UniProt
- O15511
- Pathways
- Signalisation RTK, Regulation of Actin Filament Polymerization
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