PARP1 anticorps (AA 551-620)

N° du produit ABIN6944423

Cet anticorps anti-PARP1 est un anticorps Lapin Polyclonal détectant PARP1 dans WB, ELISA, ICC, IHC (p), IF (p), IF (cc) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour PARP1 anticorps (AA 551-620) (ABIN6944423)

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-PARP1 anticorps

Épitope: AA 551-620

Réactivité croisée: Humain

Homologie: Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PARP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: PARP1

Sujet:

Synonyms: ADP ribosyltransferase (NAD+, poly (ADP ribose) polymerase), ADP ribosyltransferase NAD+, ADPRT 1, ADPRT, ADPRT1, msPARP, NAD(+) ADP ribosyltransferase 1, pADPRT 1, pADPRT1, PARP 1, PARP1, PARP-1, Poly (ADP ribose) polymerase 1, poly (ADP ribose) polymerase family, member 1, Poly adenosine diphosphate ADP ribose polymerase, Poly ADP ribose polymerase 1, Poly ADP ribose polymerase family member 1, Poly ADP ribose synthetase 1, poly(ADP ribose) synthetase, poly(ADP ribosyl)transferase, Poly[ADP ribose] synthetase 1, PPOL, sPARP 1, sPARP1, PARP1_HUMAN.

Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008].

ID gène: 142

UniProt: P09874

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location