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PD-L1 anticorps

PD-L1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 6C8 unconjugated

N° du produit ABIN6944458

Fiche de données

Antigène Voir toutes PD-L1 Anticorps

PD-L1 (CD274 (PD-L1))
Reactivité
171

108

63

7

6

5

5

1

1
Humain
Hôte
127

62

17

4

4

1
Lapin
Anticorps secondaires appropriés
Clonalité
108

105

2
Monoclonal
Conjugué
99

16

13

11

9

5

5

5

5

5

5

5

4

4

4

4

4

4

3

2

1

1

1
Cet anticorp PD-L1 est non-conjugé
Application
139

104

60

40

38

28

17

17

16

15

10

7

5

5

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Flow Cytometry (FACS)

Réactivité croisée

Humain

Purification

Purified by Protein A.

Immunogène

Recombinant human PD-L1 extracellular domain

Clone

6C8

Isotype

IgG

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PD-L1 Reactivité: Humain IHC Hôte: Lapin Monoclonal unconjugated

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PD-L1 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

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KO Validated PD-L1 Reactivité: Humain WB, FACS, ICC, IF, IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

Indications d'application

WB 1:300-5000
FCM 1:20-100

Restrictions

For Research Use only
Format

Liquid

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C for 12 months.

Date de péremption

12 months
Antigène

PD-L1 (CD274 (PD-L1))

Autre désignation

PD-L1 (PD-L1 Produits)

Synonymes

anticorps B7-H, anticorps B7H1, anticorps PD-L1, anticorps PDCD1L1, anticorps PDCD1LG1, anticorps PDL1, anticorps A530045L16Rik, anticorps B7h1, anticorps Pdcd1l1, anticorps Pdcd1lg1, anticorps Pdl1, anticorps RGD1566211, anticorps CD274 molecule, anticorps CD274 antigen, anticorps programmed cell death 1 ligand 2, anticorps CD274, anticorps Cd274, anticorps PDCD1LG2

Sujet

Synonyms: Programmed cell death 1 ligand 1, CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1, Programmed death ligand 1
Background: Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/CD279, modulates the activation threshold of T-cells and limits T-cell effector response (PubMed:11015443). The PDCD1/CD279-mediated inhibitory pathway is exploited by tumors to attenuate anti-tumor immunity and facilitate tumor survival (PubMed:28813417, PubMed:28813410). Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10) (PubMed:10581077).

ID gène

29126

UniProt

Q9NZQ7

Pathways

Cancer Immune Checkpoints