Histone 3 anticorps (acLys9)
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- Antigène Voir toutes Histone 3 (H3) Anticorps
- Histone 3 (H3)
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Épitope
- acLys9
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Reactivité
- Humain, Souris
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp Histone 3 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)
- Attributs du produit
- Histone H3 is one of the core components of the nucleosome, the basic building block of chromatin. Histones are subject to a variety of chemical modifications, including post-translational modifications of the histone proteins and the methylation of cytosine residues in the DNA. Reported histone modifications include acetylation, methylation, phosphorylation, ubiquitylation, glycosylation, ADP-ribosylation, carbonylation and SUMOylation, these modifications play a major role in regulating gene expression. Acetylation of Lys9 is associated with trascriptional activation of genes. Histone H3K9ac antibody (mAb) (Clone 1B10) was raised in a Mouse host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq, Dot blot, Immunocytochemistry, Immunofluorescence and Western blot, it has been shown to react with Human and Mouse samples, but it is predicted that it will react with a wide range of sample types.
- Purification
- Protein A Chromatography
- Immunogène
- The Histone H3 acetyl Lys9 antibody was raised against a peptide including acetyl-lysine 9 of human Histone H3.
- Clone
- 1B10
- Isotype
- IgG3
- Top Product
- Discover our top product H3 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Purified IgG in 0.1 M Tris, pH 8.0, 1 M NaCl with 30 % glycerol and 0.035 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry." dans: Nature, (2022) (PubMed).
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SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry." dans: Nature, (2022) (PubMed).
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- Antigène
- Histone 3 (H3)
- Autre désignation
- Histone H3 (H3 Produits)
- Synonymes
- anticorps H-3, anticorps histocompatibility 3, anticorps H3
- Poids moléculaire
- 17
- NCBI Accession
- NP_003522
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