C-JUN anticorps (AA 231-331) (AbBy Fluor® 350)

N° du produit ABIN6976884

Cet anticorps anti-C-JUN est un anticorps Lapin Polyclonal détectant C-JUN dans FACS. Adapté pour Humain.

Aperçu rapide pour C-JUN anticorps (AA 231-331) (AbBy Fluor® 350) (ABIN6976884)

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C-JUN est conjugé à/à la AbBy Fluor® 350

Application: Flow Cytometry (FACS)

Détail du produit anti-C-JUN anticorps (AbBy Fluor® 350)

Épitope: AA 231-331

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Pig,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human C-jun

Isotype: IgG

Information d'application

Indications d'application: FCM 1:20-100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur C-JUN

Antigène: C-JUN (JUN) (Jun Proto-Oncogene (JUN))

Autre désignation: C-jun

Sujet:

Synonyms: Transcription factor AP-1, Jun oncogene, JUN, AP 1, AP1, AP-1, Enhancer Binding Protein AP1, Jun Activation Domain Binding Protein, JUN protein, JUNC, p39, Proto oncogene cJun, Transcription Factor AP1, V jun avian sarcoma virus 17 oncogene homolog, vJun Avian Sarcoma Virus 17 Oncogene Homolog, JUN_HUMAN, Activator 1, Proto-oncogene c-Jun, V-jun avian sarcoma virus 17 oncogene homolog.

Background: The human protooncogene JUN is the putative transforming gene of avian sarcoma virus 17, and it encodes a protein which is highly homologous to the viral protein. cJun (previously known as the Fos binding protein p39) and c Fos form a complex in the nucleus. AP 1 (activating protein 1) is a collective term referring to these dimeric transcription factors composed of Jun, Fos or ATF subunits that bind to a common DNA site, the AP1 binding site. AP 1 proteins, mostly the Jun group, regulate the expression and function of cell cycle regulators such as Cyclin D1, p53, p21 (cip1/waf1), p19 (ARF) and p16. Fos and Jun proto oncogene expression is induced transiently by a variety of extracellular stimuli associated with mitogenesis, differentiation processes or depolarization of neurons. JUN has been mapped to 1p32 to p31, a chromosomal region involved in both translocations and deletions in human malignancies.

ID gène: 3725

UniProt: P05412

Pathways: Signalisation MAPK, Signalisation RTK, Signalisation WNT, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling, S100 Proteins