PARP1 anticorps (AA 581-650) (AbBy Fluor® 350)
Aperçu rapide pour PARP1 anticorps (AA 581-650) (AbBy Fluor® 350) (ABIN6976979)
Antigène
Voir toutes PARP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 581-650
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Réactivité croisée
- Humain, Souris, Rat
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Homologie
- Cow,Sheep,Pig,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human PARP1
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Isotype
- IgG
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Indications d'application
- FCM 1:20-100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Date de péremption
- 12 months
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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Autre désignation
- PARP1
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Sujet
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Synonyms: RANTES, CCL5, TCP228, Small Inducible Cytokine A5, CCL5, SISd, MGC17164, SCYA5, RANTES, D17S136E, SIS-delta, chemokine (C-C motif) ligand 5, regulated on activation normal T cell expressed and secreted, chemokine (C-C motif) ligand 5, T-cell-specific protein RANTES, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, RANTES(3-68), RANTES(4-68), CCL5_HUMAN,
Background: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.
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ID gène
- 6352
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UniProt
- P09874
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Pathways
- Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
Antigène
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