IMPACT anticorps (AA 21-120) (AbBy Fluor® 488)
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- Antigène Voir toutes IMPACT Anticorps
- IMPACT (Impact Homolog (IMPACT))
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Épitope
- AA 21-120
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp IMPACT est conjugé à/à la AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Souris, Rat
- Homologie
- Human,Dog,Cow,Sheep,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human IMPACT
- Isotype
- IgG
- Top Product
- Discover our top product IMPACT Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- IMPACT (Impact Homolog (IMPACT))
- Autre désignation
- IMPACT (IMPACT Produits)
- Synonymes
- anticorps zgc:103672, anticorps Ximpact, anticorps impact-A, anticorps RWDD5, anticorps impact-a, anticorps E430016J11Rik, anticorps impact RWD domain protein, anticorps impact, anticorps impact RWD domain protein L homeolog, anticorps impact, RWD domain protein, anticorps IMPACT, anticorps impact, anticorps EDI_298310, anticorps impact.L, anticorps Impact
- Sujet
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Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog
Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).
- ID gène
- 55364
- UniProt
- Q9P2X3
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