NMDAR2A anticorps (pSer1232) (AbBy Fluor® 594)
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- Antigène Voir toutes NMDAR2A (GRIN2A) Anticorps
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
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Épitope
- pSer1232
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NMDAR2A est conjugé à/à la AbBy Fluor® 594
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificité
- This phosphorylated site is homologous to that of Ser1232 in Mouse and Rat.
- Homologie
- Human,Mouse,Rat,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated Synthesised phosphopeptide derived from human NMDAR2A around the phosphorylation site of Ser1232
- Isotype
- IgG
- Top Product
- Discover our top product GRIN2A Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
- Autre désignation
- NMDAR2A (GRIN2A Produits)
- Synonymes
- anticorps NMDAR2A, anticorps nr2a, anticorps GRIN2A, anticorps EPND, anticorps GluN2A, anticorps NR2A, anticorps glutamate ionotropic receptor NMDA type subunit 2A, anticorps glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog, anticorps glutamate receptor ionotropic, NMDA 2A, anticorps glutamate receptor, ionotropic, NMDA2A (epsilon 1), anticorps GRIN2A, anticorps grin2a.L, anticorps LOC100438553, anticorps Grin2a
- Sujet
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Synonyms: NMDAR2A (phospho S1232), p-NMDAR2A (phospho S1232), GRIN2B, Glutamate [NMDA] receptor subunit epsilon 1, Glutamate [NMDA] receptor subunit epsilon 2, Glutamate [NMDA] receptor subunit epsilon-1, Glutamate [NMDA] receptor subunit epsilon-2, GRIN2A, hNR2A, hNR3, N methyl D aspartate receptor subtype 2A, N methyl D aspartate receptor subtype 2B, N-methyl D-aspartate receptor subtype 2A, N-methyl D-aspartate receptor subtype 2B, N-methyl-D-aspartate receptor subunit 3, NMDAR2A, NMDAR2B, NMDE2_HUMAN, NR2A, NR2B, NR3.
Background: This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.
- ID gène
- 2903
- UniProt
- Q12879
- Pathways
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
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