TNFRSF6B anticorps (N-Term)

N° du produit ABIN6990301

Détail du produit anti-TNFRSF6B anticorps

Antigène: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF6B est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: DcR3 Antibody is Ion exchange chromatography purified.

Immunogène: DcR3 antibody was raised against a peptide corresponding to amino acids near the amino terminus of human DcR3 precursor. The immunogen is located within the first 50 amino acids of DcR3.

Isotype: IgG

Information d'application

Indications d'application: DcR3 antibody can be used for detection of DcR3 expression by Western blot 0.5 μ,g/mL. An approximately 33 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 1 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: DcR3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: DcR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur TNFRSF6B

Antigène: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Autre désignation: DcR3 (TNFRSF6B Produits)

Synonymes: anticorps DCR3, anticorps DJ583P15.1.1, anticorps M68, anticorps M68E, anticorps TR6, anticorps dcr3, anticorps m68, anticorps tr6, anticorps TNF receptor superfamily member 6b, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps regulator of telomere elongation helicase 1, anticorps TNF receptor superfamily member 6b L homeolog, anticorps TNFRSF6B, anticorps tnfrsf11b, anticorps RTEL1, anticorps tnfrsf6b, anticorps tnfrsf6b.L

Sujet: DcR3 Antibody: Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively,. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Poids moléculaire: 33 kDa

ID gène: 8771

UniProt: O95407