TNFRSF6B anticorps

N° du produit ABIN7076071

Détail du produit anti-TNFRSF6B anticorps

Antigène: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFRSF6B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Souris, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Human DcR3

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000, IHC/IF (H,M,R) 1:700-1:1400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TNFRSF6B

Antigène: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Autre désignation: DcR3 (TNFRSF6B Produits)

Synonymes: anticorps DCR3, anticorps DJ583P15.1.1, anticorps M68, anticorps M68E, anticorps TR6, anticorps dcr3, anticorps m68, anticorps tr6, anticorps TNF receptor superfamily member 6b, anticorps tumor necrosis factor receptor superfamily, member 11b, anticorps regulator of telomere elongation helicase 1, anticorps TNF receptor superfamily member 6b L homeolog, anticorps TNFRSF6B, anticorps tnfrsf11b, anticorps RTEL1, anticorps tnfrsf6b, anticorps tnfrsf6b.L

Sujet: Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1and DcR2, DcR3 is a soluble rather than a membraneassociated molecule. DcR3 binds to FasL and LIGHT andinhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and coloncarcinomas and in some normal tissues.

Poids moléculaire: 33 kDa

ID gène: 8771

NCBI Accession: NP_003814

UniProt: O95407