ANO1 anticorps (N-Term)
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- Antigène Voir toutes ANO1 Anticorps
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
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Épitope
- AA 70-120, N-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ANO1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- TMEM16A Antibody is affinity chromatography purified via peptide column.
- Immunogène
- TMEM16A antibody was raised against a 17 amino acid synthetic peptide from near the amino terminus of human TMEM16A. The immunogen is located within amino acids 70 - 120 of TMEM16A.
- Isotype
- IgG
- Top Product
- Discover our top product ANO1 Anticorps primaire
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- Indications d'application
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TMEM16A antibody can be used for detection of TMEM16A by Western blot at 1 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- TMEM16A Antibody is supplied in PBS containing 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,4 °C
- Stockage commentaire
- TMEM16A antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- Antigène
- ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
- Autre désignation
- TMEM16A (ANO1 Produits)
- Synonymes
- anticorps DOG1, anticorps ORAOV2, anticorps TAOS2, anticorps TMEM16A, anticorps Tmem16a, anticorps anoctamin 1, anticorps anoctamin 1, calcium activated chloride channel, anticorps Ano1, anticorps ANO1
- Sujet
- TMEM16A Antibody: Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC's include the transmembrane proteins TMEM16A and TMEM16B. TMEM16A is expressed in epithelial cells of the kidney and lung, pancreas, and sensory neurons and its mRNA is seen in foregut, airway epithelia, and tracheal smooth muscle, mice lacking TMEM16A fail to survive past ten days and show aerophagia and little weight gain. TMEM16A is also overexpressed or amplified in multiple cancers associated with poor survival such as oral cancers and gastrointestinal stromal tumors, suggesting the development of CaCC modulators may be a viable therapeutic strategy.
- ID gène
- 55107
- NCBI Accession
- NP_060513
- UniProt
- Q5XXA6
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