SLC39A3 anticorps (AA 110-160)

N° du produit ABIN6991453

Détail du produit anti-SLC39A3 anticorps

Antigène: SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))

Épitope: AA 110-160

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC39A3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: ZIP3 Antibody is affinity chromatography purified via peptide column.

Immunogène: ZIP3 antibody was raised against a 16 amino acid synthetic peptide near the center of human ZIP3. The immunogen is located within amino acids 110 - 160 of ZIP3.

Isotype: IgG

Information d'application

Indications d'application: ZIP3 antibody can be used for detection of ZIP3 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.

Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: ZIP3 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: ZIP3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur SLC39A3

Antigène: SLC39A3 (Solute Carrier Family 39 (Zinc Transporter), Member 3 (SLC39A3))

Autre désignation: ZIP3 (SLC39A3 Produits)

Synonymes: anticorps AI845814, anticorps Zip3, anticorps ZIP3, anticorps wu:fc84e09, anticorps zgc:158334, anticorps solute carrier family 39 (zinc transporter), member 3, anticorps solute carrier family 39 member 3, anticorps Slc39a3, anticorps slc39a3, anticorps SLC39A3

Sujet: ZIP3 Antibody: The zinc transporter ZIP3, also known as SLC39A3, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. Similar to knock-outs of ZIP1 and ZIP2, ZIP3-null mice have no phenotypic differences compared to wild-type mice. Only when ZIP1, ZIP2, and ZIP3 genes are all eliminated and these mutant mice are fed a zinc-deficient diet do abnormalities such as reduced embryonic-membrane bound alkaline phosphatase activity and abnormal development occur, indicating that the ZIP1-3 proteins play an important, noncompensatory role when zinc is deficient. More recent studies have shown that ZIP2 and ZIP3 are down regulated in human prostate adenocarcinomatous glands, and may be important in the retention of zinc in the cellular compartment.

ID gène: 29985

NCBI Accession: NP_653165

UniProt: Q9BRY0

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy