LRRFIP2 anticorps (C-Term)

N° du produit ABIN6991500

Détail du produit anti-LRRFIP2 anticorps

Antigène: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Épitope: AA 620-670, C-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LRRFIP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Specificité: Three isoforms of LRRFIP2 are known to exist, this antibody will recognize all three. LRRFIP2 antibody is predicted to not cross-react with other LRRFIP family members.

Purification: LRRFIP2 Antibody is affinity chromatography purified via peptide column.

Immunogène: LRRFIP2 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human LRRFIP2. The immunogen is located within amino acids 620 - 670 of LRRFIP2.

Isotype: IgG

Information d'application

Indications d'application: LRRFIP2 antibody can be used for detection of LRRFIP2 by Western blot at 0.5 and 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: LRRFIP2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: LRRFIP2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur LRRFIP2

Antigène: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Autre désignation: LRRFIP2 (LRRFIP2 Produits)

Synonymes: anticorps HUFI-2, anticorps 5133400F20Rik, anticorps AI850587, anticorps wu:fj34c02, anticorps zgc:113956, anticorps zgc:63771, anticorps LRR binding FLII interacting protein 2, anticorps leucine rich repeat (in FLII) interacting protein 2, anticorps leucine rich repeat (in FLII) interacting protein 2 L homeolog, anticorps LRRFIP2, anticorps Lrrfip2, anticorps lrrfip2, anticorps lrrfip2.L

Sujet: LRRFIP2 Antibody: The leucine-rich repeat FLI-I-interacting protein 2 (LRRFIP2), like the related protein LRRFIP1, was identified in a yeast two-hybrid system through binding to the LRR domain of human FLI. It can activate the Wnt signaling pathway in cultured cells and is thought to be a component of the Wnt signaling pathway that modulates Wnt signaling through interactions with Disheveled to increase the cellular levels and transcription activity of beta-catenin. LRRFIP2 has recently been characterized as a positive regulator of the TLR4 signaling pathway for activating NF-κ,B during the early host response to LPS stimulation through binding to the TLR adaptor protein MyD88, and that this interaction with MyD88 is governed by phosphorylation of specific residues in LRRFIP2.

ID gène: 9209

NCBI Accession: NP_006300

UniProt: Q9Y608