PTRF anticorps (C-Term)

N° du produit ABIN6991834

Détail du produit anti-PTRF anticorps

Antigène: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Épitope: AA 270-320, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTRF est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: At least three isoforms of PTRF are known to exist, this antibody detects all three isoforms. It is predicted to not cross-react with other members of the cavin family.

Purification: PTRF Antibody is affinity chromatography purified via peptide column.

Immunogène: Rabbit polyclonal PTRF antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PTRF. The immunogen is located within amino acids 270 - 320 of PTRF.

Isotype: IgG

Information d'application

Indications d'application: PTRF antibody can be used for detection of PTRF by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PTRF Antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: PTRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur PTRF

Antigène: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Autre désignation: PTRF (PTRF Produits)

Synonymes: anticorps MGC53017, anticorps MGC89141, anticorps PTRF, anticorps fd20g07, anticorps ptrf, anticorps wu:fd20g07, anticorps zgc:162917, anticorps CAVIN, anticorps CAVIN1, anticorps CGL4, anticorps cavin-1, anticorps 2310075E07Rik, anticorps AW546441, anticorps Cav-p60, anticorps Cavin, anticorps caveolae associated protein 1 L homeolog, anticorps polymerase I and transcript release factor, anticorps caveolae associated protein 1, anticorps caveolae associated protein 1b, anticorps caveolae associated 1, anticorps cavin1.L, anticorps PTRF, anticorps cavin1, anticorps CAVIN1, anticorps cavin1b, anticorps Cavin1

Sujet: PTRF Antibody: The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.

Poids moléculaire: 43 kDa

ID gène: 284119

NCBI Accession: NP_036364

UniProt: Q6NZI2