TESPA1 anticorps (N-Term)

N° du produit ABIN6991940

Détail du produit anti-TESPA1 anticorps

Antigène: TESPA1 (Thymocyte Expressed, Positive Selection Associated 1 (TESPA1))

Épitope: AA 20-70, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TESPA1 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: TESPA1 antibody is human specific. At least three isoforms TESPA1 are known to exist.

Purification: TESPA1 antibody is affinity chromatography purified via peptide column.

Immunogène: TESPA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human TESPA1. The immunogen is located within amino acids 20 - 70 of TESPA1.

Isotype: IgG

Information d'application

Indications d'application: TESPA1 antibody can be used for detection of TESPA1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunocytochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: TESPA1 antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: TESPA1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur TESPA1

Antigène: TESPA1 (Thymocyte Expressed, Positive Selection Associated 1 (TESPA1))

Autre désignation: TESPA1 (TESPA1 Produits)

Synonymes: anticorps KIAA0748, anticorps thymocyte expressed, positive selection associated 1, anticorps TESPA1

Sujet: TESPA1 is a critical component of the TCR signalosome and is essential for T cell selection and maturation through the regulation of TCR signaling during T cell development (1). TESPA1 encodes a protein of 458 amino acids and is highly conserved among vertebrate species (2). TESPA1 expression was tightly regulated during T cell development, with highest expression at the DP stage (3). TESPA1 deficiency resulted in failure of positive selection and substantially fewer of CD4+ and CD8+ SP cells in the thymus (1,4).

Poids moléculaire: Predicted: 57 kDa

Observed: 60 kDa

ID gène: 9840

NCBI Accession: NP_001129502

UniProt: A2RU30