VISTA anticorps (Extracellular Domain)

N° du produit ABIN6992256

Détail du produit anti-VISTA anticorps

Antigène: VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))

Épitope: Extracellular Domain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp VISTA est non-conjugé

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Purification: VISTA Antibody is supplied as protein A purified IgG1.

Immunogène: VISTA antibody was raised against the extracellular domain of human VISTA.

Clone: 4C4

Isotype: IgG1

Information d'application

Indications d'application: VISTA antibody can be used for detection of VISTA by Western blot at 0.25 - 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2 μ,g/mL and immunocytochemistry starting at 1 μ,g/mL. For immunofluorescence start at 2 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples, Immunocytochemistry in human samples, Immunofluorescence in human samples and Flow Cytometry in mouse samples. All other applications and species not yet tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: VISTA Antibody is supplied in PBS containing 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: VISTA antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Détails sur VISTA

Antigène: VISTA (V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA))

Autre désignation: VISTA (VISTA Produits)

Synonymes: anticorps MGC112715, anticorps MGC151567, anticorps B7-H5, anticorps B7H5, anticorps GI24, anticorps PP2135, anticorps SISP1, anticorps Dies1, anticorps VISTA, anticorps V-set immunoregulatory receptor, anticorps vsir, anticorps Vsir, anticorps VSIR

Sujet: VISTA Antibody: VISTA/B7-H5/platelet receptor Gi24 is a single-pass type I membrane protein located at the cell surface. It is an immunoregulatory receptor which can inhibit T-cell response and may promote differentiation of embryonic stem cells, by inhibiting the BMP4 signaling pathway. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation.

Poids moléculaire: Predicted: 31 kDa

Observed: 47 kDa

ID gène: 64115

NCBI Accession: NP_071436

UniProt: Q9H7M9

Pathways: Cancer Immune Checkpoints