Lamin B1 anticorps

N° du produit ABIN7245590

Détail du produit anti-Lamin B1 anticorps

Antigène: Lamin B1 (LMNB1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Fusion protein of human LMNB1

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:5000, IHC 1:100-1:300, ELISA 1:2000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Lamin B1

Antigène: Lamin B1 (LMNB1)

Autre désignation: LMNB1 (LMNB1 Produits)

Synonymes: anticorps MGC52550, anticorps Lamin-L(I), anticorps lamin-b, anticorps lmn, anticorps lmn2, anticorps lmnb, anticorps LMNB1, anticorps ADLD, anticorps LMN, anticorps LMN2, anticorps LMNB, anticorps fc06g01, anticorps wu:fc06g01, anticorps lamin B1 L homeolog, anticorps lamin B1, anticorps lmnb1.L, anticorps lmnb1, anticorps LMNB1, anticorps Lmnb1

Sujet: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Poids moléculaire:

Observed_MW: Refer to figures

Calculated_MW: 67 kDa

UniProt: P20700

Pathways: Apoptose, Caspase Cascade in Apoptosis