p53 anticorps (meLys370)
Aperçu rapide pour p53 anticorps (meLys370) (ABIN7250971)
Antigène
Voir toutes p53 (TP53) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- meLys370
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Attributs du produit
- Methylated antibody
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Purification
- Protein A purification
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Immunogène
- Synthetic Peptide
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Isotype
- IgG
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Indications d'application
- IHC 1:50-1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.4.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- p53 (TP53) (Tumor Protein P53 (TP53))
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Autre désignation
- P53
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Sujet
- The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
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UniProt
- P04637
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Pathways
- Signalisation p53, Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, L'effet Warburg
Antigène
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