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ERK1/2 anticorps (pTyr205, pTyr222)

MAPK1/3 Reactivité: Humain, Souris, Rat IHC (p) Hôte: Souris Monoclonal 4D4 unconjugated
N° du produit ABIN7005808
  • Antigène Voir toutes ERK1/2 (MAPK1/3) Anticorps
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Épitope
    • 56
    • 41
    • 30
    • 30
    • 16
    • 12
    • 12
    • 10
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr205, pTyr222
    Reactivité
    • 199
    • 169
    • 166
    • 22
    • 22
    • 18
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 143
    • 58
    • 4
    Souris
    Clonalité
    • 139
    • 66
    Monoclonal
    Conjugué
    • 99
    • 12
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ERK1/2 est non-conjugé
    Application
    • 157
    • 65
    • 51
    • 51
    • 49
    • 38
    • 24
    • 23
    • 22
    • 13
    • 7
    • 4
    • 4
    • 3
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Attributs du produit
    Phosphorylated antibody
    Purification
    Protein A purification
    Immunogène
    Synthetic Peptide of Phospho-ERK 1/2 (Tyr222/205)
    Clone
    4D4
    Isotype
    IgG
    Top Product
    Discover our top product MAPK1/3 Anticorps primaire
  • Indications d'application
    IHC 1:100-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    ERK1/2 (MAPK1/3) (Mitogen-Activated Protein Kinase 1/3 (MAPK1/3))
    Autre désignation
    ERK 1/2 (MAPK1/3 Produits)
    Synonymes
    anticorps erk1/2, anticorps mitogen-activated protein kinase, anticorps erk1/2
    Sujet
    Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1, required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2.Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.
    UniProt
    P27361, P28482
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