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Caspase 1 anticorps (Cleaved-Asp210)

CASP1 Reactivité: Humain WB, ELISA, IHC (p), IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7251010
  • Antigène Voir toutes Caspase 1 (CASP1) Anticorps
    Caspase 1 (CASP1)
    Épitope
    • 8
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cleaved-Asp210
    Reactivité
    • 93
    • 36
    • 29
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 103
    • 11
    • 4
    • 1
    Lapin
    Clonalité
    • 94
    • 25
    Polyclonal
    Conjugué
    • 80
    • 18
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Caspase 1 est non-conjugé
    Application
    • 90
    • 47
    • 44
    • 23
    • 14
    • 13
    • 11
    • 6
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Attributs du produit
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogène
    Synthesized peptide derived from the Internal region of human Caspase-1
    Isotype
    IgG
    Top Product
    Discover our top product CASP1 Anticorps primaire
  • Indications d'application
    WB 1:500-2000, IHC 1:50-300, IF 1:50-300
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20°C. Avoid freeze / thaw cycles.
  • Antigène
    Caspase 1 (CASP1)
    Autre désignation
    CASP1 (CASP1 Produits)
    Synonymes
    anticorps ICE, anticorps IL1BC, anticorps P45, anticorps Il1bc, anticorps Ice, anticorps CASP1, anticorps CG5370, anticorps DCP-1, anticorps DCP1, anticorps Dcp1, anticorps Dmel\\CG5370, anticorps ccp1, anticorps dcp-1, anticorps dcp1, anticorps l(2)01862, anticorps l(2)02132, anticorps caspase 1, anticorps caspase 1, apoptosis-related cysteine peptidase, anticorps caspase 4, apoptosis-related cysteine peptidase, anticorps Death caspase-1, anticorps caspase-1, anticorps caspase, anticorps caspase recruitment domain-containing protein 16, anticorps caspase 4, anticorps CASP1, anticorps Casp1, anticorps CASP4, anticorps Dcp-1, anticorps Caspase1, anticorps LOC5564196, anticorps LOC451519
    Sujet
    Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
    Poids moléculaire

    Observed_MW: 25 kDa

    Calculated_MW: 45 kDa

    UniProt
    P29466
    Pathways
    Apoptose, Interferon-gamma Pathway, Positive Regulation of Endopeptidase Activity, Inflammasome
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