PARP1 anticorps (Cleaved-Asp214)

N° du produit ABIN7251022

L’anticorps Lapin Polyclonal anti-PARP1 a été validé pour WB, ELISA, IF et IHC (p). Il convient pour détecter PARP1 dans des échantillons de Humain et Souris.

Aperçu rapide pour PARP1 anticorps (Cleaved-Asp214) (ABIN7251022)

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PARP1 anticorps

Épitope: Cleaved-Asp214

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Synthesized peptide derived from the Internal region of human PARP-1

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PARP1

Antigène: PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

Autre désignation: PARP1

Sujet: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Poids moléculaire:

Observed_MW: 24 kDa

Calculated_MW: 113 kDa

UniProt: P09874

Pathways: Apoptose, Caspase Cascade in Apoptosis, Réparation de l'ADN, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location