APC anticorps

N° du produit ABIN7260669

Détail du produit anti-APC anticorps

Antigène: APC (Adenomatous Polyposis Coli (APC))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APC est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human APC (NP_000029.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200 IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur APC

Antigène: APC (Adenomatous Polyposis Coli (APC))

Autre désignation: APC (APC Produits)

Synonymes: anticorps dp2, anticorps dp3, anticorps fap, anticorps fpc, anticorps xapc, anticorps dp2.5, anticorps AI047805, anticorps AU020952, anticorps AW124434, anticorps CC1, anticorps Min, anticorps mAPC, anticorps BTPS2, anticorps DP2, anticorps DP2.5, anticorps DP3, anticorps GS, anticorps PPP1R46, anticorps RATAPC, anticorps APC1, anticorps APC, WNT signaling pathway regulator, anticorps adenomatous polyposis coli, anticorps adenomatous polyposis coli protein, putative, anticorps adenomatosis polyposis coli, anticorps adenomatous polyposis coli L homeolog, anticorps APC, anticorps apc, anticorps Smp_139190, anticorps Apc, anticorps apc.L

Sujet: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

ID gène: 324

UniProt: P25054

Pathways: Signalisation WNT, Stem Cell Maintenance, Cell-Cell Junction Organization