Cyclin A1 anticorps

N° du produit ABIN7261576

Détail du produit anti-Cyclin A1 anticorps

Antigène: Cyclin A1 (CCNA1)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin A1 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human CCNA1 (NP_001104515.1).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Cyclin A1

Antigène: Cyclin A1 (CCNA1)

Autre désignation: CCNA1 (CCNA1 Produits)

Synonymes: anticorps fd14f08, anticorps wu:fd14f08, anticorps wu:fi20d12, anticorps zgc:111869, anticorps MGC81965, anticorps cyclin-A1, anticorps CCNA1, anticorps MGC132235, anticorps cyclin-A1-2, anticorps Cyclin-A1, anticorps ccna1, anticorps cyclin A1, anticorps cyclin A1 L homeolog, anticorps CYCLIN A1;2, anticorps cyclin A1 S homeolog, anticorps CCNA1, anticorps ccna1, anticorps ccna1.L, anticorps CYCA1;2, anticorps Ccna1, anticorps ccna1.S

Sujet: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire:

Observed_MW: 52 kDa

Calculated_MW: 47 kDa/52 kDa

ID gène: 8900

UniProt: P78396

Pathways: Apoptose, Cycle Cellulaire, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA