CYP11A1 anticorps (AA 321-420)
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- Antigène Voir toutes CYP11A1 Anticorps
- CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
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Épitope
- AA 321-420
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Reactivité
- Humain, Rat, Souris, Boeuf (Vache)
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CYP11A1 est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Boeuf (Vache), Humain, Souris, Rat
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human CYP11A1/P450SCC
- Isotype
- IgG
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- Indications d'application
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." dans: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).
: "Dual effects of sulfasalazine on rat sperm characteristics, spermatogenesis, and steroidogenesis in two experimental models." dans: Toxicology letters, Vol. 284, pp. 46-55, (2018) (PubMed).
: "Prenatal exposure to bisphenol A disrupts adrenal steroidogenesis in adult mouse offspring." dans: Environmental toxicology and pharmacology, Vol. 43, pp. 203-8, (2016) (PubMed).
: "Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis." dans: Cell reports, Vol. 7, Issue 4, pp. 1130-42, (2014) (PubMed).
: "Low-dose monobutyl phthalate stimulates steroidogenesis through steroidogenic acute regulatory protein regulated by SF-1, GATA-4 and C/EBP-beta in mouse Leydig tumor cells." dans: Reproductive biology and endocrinology : RB&E, Vol. 11, pp. 72, (2013) (PubMed).
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Application of rat cryptorchidism model for the evaluation of mesenchymal stromal cell secretome regenerative potential." dans: Biomedicine & pharmacotherapy, Vol. 109, pp. 1428-1436, (2019) (PubMed).
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- Antigène
- CYP11A1 (Cytochrome P450, Family 11, Subfamily A, Polypeptide 1 (CYP11A1))
- Autre désignation
- CYP11A1 (CYP11A1 Produits)
- Synonymes
- anticorps CYP11A, anticorps CYP11A1, anticorps CYPXIA1, anticorps P450SCC, anticorps Cyp11a, anticorps Cypxia1, anticorps D9Ertd411e, anticorps P450scc, anticorps Scc, anticorps cscc, anticorps P450(scc), anticorps SSC, anticorps cytochrome P450 family 11 subfamily A member 1, anticorps cholesterol side-chain cleavage enzyme, mitochondrial-like, anticorps cytochrome P450 cholesterol side-chain cleavage, anticorps cytochrome P450, family 11, subfamily a, polypeptide 1, anticorps cytochrome P450, family 11, subfamily A, polypeptide 1, anticorps CYP11A1, anticorps LOC101827747, anticorps Cyp11a1
- Sujet
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Synonyms: CYP11A, CYPXIA1, P45SCC, Cholesterol side-chain cleavage enzyme, mitochondrial, Cholesterol desmolase, Cytochrome P45 11A1, Cytochrome P45(scc), CYP11A1
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq, Jul 2008]
- ID gène
- 1583
- UniProt
- P05108
- Pathways
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Cellular Response to Molecule of Bacterial Origin
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