RPS6KB2 anticorps (pSer447, pThr444)

N° du produit ABIN702850

Détail du produit anti-RPS6KB2 anticorps

Antigène: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Épitope: pSer447, pThr444

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPS6KB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human p70 S6 Kinase Beta around the phosphorylation site of Thr444/Ser447

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur RPS6KB2

Antigène: RPS6KB2 (Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 2 (RPS6KB2))

Autre désignation: p70 S6 Kinase Beta + (RPS6KB2 Produits)

Synonymes: anticorps KLS, anticorps P70-beta, anticorps P70-beta-1, anticorps P70-beta-2, anticorps S6K-beta2, anticorps S6K2, anticorps SRK, anticorps STK14B, anticorps p70(S6K)-beta, anticorps p70S6Kb, anticorps 70kDa, anticorps ribosomal protein S6 kinase B2, anticorps ribosomal protein S6 kinase, polypeptide 2, anticorps RPS6KB2, anticorps Rps6kb2

Sujet:

Synonyms: p70 S6 KinaseThr444 + Ser447, P70 S6 Kinase beta phospho T444 + S447, 70 kDa ribosomal protein S6 kinase 2, p70 beta, p70 ribosomal S6 kinase beta, p70 S6 kinase beta, p70 S6KB, p70 S6Kbeta, p70S6K beta, p70-beta, p70-S6KB, p70S6Kb, Ribosomal protein S6 kinase 70 kDa, polypeptide 2, Ribosomal protein S6 kinase beta 2, Ribosomal protein S6 kinase beta-2, RPS6KB2, S6 kinase related kinase, S6 kinase-related kinase, S6K beta 2, S6K beta, S6K-beta, S6K2, Serine/threonine protein kinase 14 beta, Serine/threonine-protein kinase 14 beta, SRK, STK14B, KS6B1_HUMAN.

Background: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013].

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway