Deltex Homolog 1 anticorps
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- Antigène Voir toutes Deltex Homolog 1 (DTX1) Anticorps
- Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Deltex Homolog 1 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse DTX1
- Top Product
- Discover our top product DTX1 Anticorps primaire
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- Indications d'application
- IHC/IF (H,M,R) 1:600-1:1200/1:200-1:600
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- Deltex Homolog 1 (DTX1) (E3 Ubiquitin-protein ligase DTX1 (DTX1))
- Autre désignation
- DTX1 (DTX1 Produits)
- Synonymes
- anticorps hDx-1, anticorps Fxit1, anticorps mKIAA4160, anticorps deltex, anticorps dtx, anticorps xdtx1, anticorps deltex E3 ubiquitin ligase 1, anticorps deltex homolog 1 (Drosophila), anticorps deltex 1, E3 ubiquitin ligase, anticorps deltex 1 L homeolog, anticorps deltex 1 S homeolog, anticorps DTX1, anticorps dtx1, anticorps Dtx1, anticorps dtx1.L, anticorps dtx1.S
- Sujet
- The Deltex homolog 1 (E3 ubiquitin-protein ligase DTX1) functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context.
- ID gène
- 14357
- NCBI Accession
- NP_032078
- UniProt
- Q61010
- Pathways
- Signalisation Notch
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