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NOTCH4 anticorps

NOTCH4 Reactivité: Humain IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7074863
  • Antigène Voir toutes NOTCH4 Anticorps
    NOTCH4 (Notch 4 (NOTCH4))
    Reactivité
    • 44
    • 31
    • 20
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Humain
    Hôte
    • 55
    • 3
    • 3
    • 2
    • 2
    Lapin
    Clonalité
    • 49
    • 16
    Polyclonal
    Conjugué
    • 33
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NOTCH4 est non-conjugé
    Application
    • 29
    • 17
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    Affinity purification
    Immunogène
    KLH conjugated Synthetic peptide corresponding to Mouse NOTCH4
    Top Product
    Discover our top product NOTCH4 Anticorps primaire
  • Indications d'application
    IHC/IF (H) 1:600-1:1200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    NOTCH4 (Notch 4 (NOTCH4))
    Autre désignation
    Notch4 (NOTCH4 Produits)
    Synonymes
    anticorps INT3, anticorps NOTCH3, anticorps Int-3, anticorps Int3, anticorps N4, anticorps Notch4, anticorps notch 4, anticorps neurogenic locus notch homolog protein 4, anticorps NOTCH4, anticorps Notch4, anticorps LOC100712850
    Sujet
    Notch4 is a member of the Notch family. The Notch4 signaling network is an evolutionarily conserved intracellular pathway that regulates physical cell to cell interactions. The Notch4 protein, once cleaved from the trans-Golgi network, is presented on the cell surface as a heterodimer. Notch4 regulates cell-fate determination as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1. In Drosophila, once these ligands are activated via the release of the notch intracellular domain (NICD), Notch4 forms a transcriptional activator complex with RBPJ/RBPSUH which then activates the genes of the Enhancer of Split (E(spl)) locus. Notch4 also plays a role in vascular, renal and hepatic development, the implementation of differentiation, proliferation and apoptotic programs, and the regulation of branching morphogenesis in the development of the vascular system.
    ID gène
    18132
    NCBI Accession
    NP_035059
    UniProt
    P31695
    Pathways
    Signalisation Notch
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