NOTCH4 anticorps
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- Antigène Voir toutes NOTCH4 Anticorps
- NOTCH4 (Notch 4 (NOTCH4))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NOTCH4 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- Affinity purification
- Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse NOTCH4
- Top Product
- Discover our top product NOTCH4 Anticorps primaire
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- Indications d'application
- IHC/IF (H) 1:600-1:1200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- NOTCH4 (Notch 4 (NOTCH4))
- Autre désignation
- Notch4 (NOTCH4 Produits)
- Synonymes
- anticorps INT3, anticorps NOTCH3, anticorps Int-3, anticorps Int3, anticorps N4, anticorps Notch4, anticorps notch 4, anticorps neurogenic locus notch homolog protein 4, anticorps NOTCH4, anticorps Notch4, anticorps LOC100712850
- Sujet
- Notch4 is a member of the Notch family. The Notch4 signaling network is an evolutionarily conserved intracellular pathway that regulates physical cell to cell interactions. The Notch4 protein, once cleaved from the trans-Golgi network, is presented on the cell surface as a heterodimer. Notch4 regulates cell-fate determination as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1. In Drosophila, once these ligands are activated via the release of the notch intracellular domain (NICD), Notch4 forms a transcriptional activator complex with RBPJ/RBPSUH which then activates the genes of the Enhancer of Split (E(spl)) locus. Notch4 also plays a role in vascular, renal and hepatic development, the implementation of differentiation, proliferation and apoptotic programs, and the regulation of branching morphogenesis in the development of the vascular system.
- ID gène
- 18132
- NCBI Accession
- NP_035059
- UniProt
- P31695
- Pathways
- Signalisation Notch
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