SPATA13 anticorps

N° du produit ABIN7075700

Détail du produit anti-SPATA13 anticorps

Antigène: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SPATA13 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse Asef2

Information d'application

Indications d'application: WB (H) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SPATA13

Antigène: SPATA13 (Spermatogenesis Associated 13 (SPATA13))

Autre désignation: Asef2 (SPATA13 Produits)

Synonymes: anticorps ARHGEF29, anticorps ASEF2, anticorps C79050, anticorps ESTM11, anticorps X83327, anticorps mFLJ00298, anticorps spermatogenesis associated 13, anticorps SPATA13, anticorps Spata13

Sujet: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Poids moléculaire: 75 kDa

ID gène: 219140

NCBI Accession: NP_001028444

UniProt: Q5DU57