Caspase 9 anticorps (AA 141-392)

N° du produit ABIN7112370

Cet anticorps anti-Caspase 9 est un anticorps Souris Monoclonal détectant Caspase 9 dans WB, IHC, ELISA, IF et IP. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour Caspase 9 anticorps (AA 141-392) (ABIN7112370)

Antigène: Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Caspase 9 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: 1F9

Détail du produit anti-Caspase 9 anticorps

Épitope: AA 141-392

Fonction: CASP9 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 141-392aa

Immunogen: caspase 9, apoptosis-related cysteine peptidase

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:100-1:400, IF: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur Caspase 9

Antigène: Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

Autre désignation: CASP9

Sujet:

Synonyms: Caspase-9 (CASP-9)|Apoptotic protease Mch-6|Apoptotic protease-activating factor 3 (APAF-3)|ICE-like apoptotic protease 6 (ICE-LAP6)|Caspase-9 subunit p35|Caspase-9 subunit p10|CASP9|MCH6

Background: Caspase 9, apoptosis-related cysteine protease(CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1, this step is thought to be one of the earliest in the caspase activation cascade

Poids moléculaire: 46 kDa, 36 kDa

ID gène: 842

UniProt: P55211

Pathways: Signalisation MAPK, Signalisation RTK, Apoptose, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity