CD44 anticorps

N° du produit ABIN7112500

Détail du produit anti-CD44 anticorps

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: CD44 molecule(Indian blood group)

Clone: 7D6

Isotype: IgG2a

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:50-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CD44

Antigène: CD44

Autre désignation: CD44 (CD44 Produits)

Synonymes: anticorps CDW44, anticorps CSPG8, anticorps ECMR-III, anticorps HCELL, anticorps HUTCH-I, anticorps IN, anticorps LHR, anticorps MC56, anticorps MDU2, anticorps MDU3, anticorps MIC4, anticorps Pgp1, anticorps AU023126, anticorps AW121933, anticorps AW146109, anticorps HERMES, anticorps Ly-24, anticorps Pgp-1, anticorps CD44A, anticorps METAA, anticorps RHAMM, anticorps XCD44, anticorps cd44, anticorps cdw44, anticorps cspg8, anticorps ecmr-iii, anticorps hcell, anticorps lhr, anticorps mc56, anticorps mdu2, anticorps mdu3, anticorps mic4, anticorps mutch-i, anticorps pgp1, anticorps CD44 molecule (Indian blood group), anticorps syndecan 4, anticorps CD44 antigen, anticorps CD44 molecule (Indian blood group) S homeolog, anticorps CD44, anticorps SDC4, anticorps Cd44, anticorps cd44.S

Sujet: Synonyms:LHR, MDU2, MDU3, MIC4 Background:Receptor for hyaluronic acid(HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases(MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T(iTreg) cell stability and suppressive function(By similarity).

Poids moléculaire: 80-95 kDa

ID gène: 960

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling