ERCC3 anticorps

N° du produit ABIN7113553

Cet anticorps Lapin Polyclonal détecte spécifiquement ERCC3 dans WB, ELISA et IHC. Il présente une réactivité envers Humain et Souris.

Aperçu rapide pour ERCC3 anticorps (ABIN7113553)

Antigène: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ERCC3 anticorps

Fonction: ERCC3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ERCC3

Antigène: ERCC3 (DNA Repair Protein Complementing XP-B Cells (ERCC3))

Autre désignation: ERCC3

Sujet:

Synonyms: General transcription and DNA repair factor IIH helicase subunit XPB (TFIIH subunit XPB)|Basic transcription factor 2 89 kDa subunit (BTF2 p89)|DNA excision repair protein ERCC-3|DNA repair protein complementing XP-B cells|TFIIH basal transcription factor complex 89 kDa subunit (TFIIH 89 kDa subunit, TFIIH p89)|Xeroderma pigmentosum group B-complementing protein|ERCC3|XPB|XPBC

Background: This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 80 kDa

ID gène: 2071

UniProt: P19447

Pathways: Réparation de l'ADN