GSDMD anticorps

N° du produit ABIN7114492

Détail du produit anti-GSDMD anticorps

Antigène: GSDMD (Gasdermin D (GSDMD))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GSDMD est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: gasdermin D

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur GSDMD

Antigène: GSDMD (Gasdermin D (GSDMD))

Autre désignation: GSDMD (GSDMD Produits)

Synonymes: anticorps GSDMDC1, anticorps GSDMD, anticorps DF5L, anticorps DFNA5L, anticorps 1810036L03Rik, anticorps AW558049, anticorps Dfna5l, anticorps Gsdmdc1, anticorps M2-4, anticorps gasdermin D, anticorps GSDMD, anticorps Gsdmd

Sujet: Synonyms:DF5L, DFNA5L, FKSG10, FLJ12150, gasdermin D, GSDMD, GSDMDC1 Background:GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Poids moléculaire: 50-53 kDa

ID gène: 79792

UniProt: P57764

Pathways: Inflammasome