ERK1 anticorps

N° du produit ABIN7116410

L’anticorps Souris Monoclonal anti-ERK1 a été validé pour WB, IHC, ELISA et IF. Il convient pour détecter ERK1 dans des échantillons de Humain et Souris.

Aperçu rapide pour ERK1 anticorps (ABIN7116410)

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 8C11

Détail du produit anti-ERK1 anticorps

Fonction: ERK1/2 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: peptide

Immunogen: mitogen-activated protein kinase 3

Isotype: IgG1

Information d'application

Indications d'application: WB:1:500-1:5000, IHC: 1:100-1:400, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ERK1

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Autre désignation: ERK1

Sujet:

Synonyms: Mitogen-activated protein kinase 3 (MAP kinase 3, MAPK 3)|ERT2|Extracellular signal-regulated kinase 1 (ERK-1)|Insulin-stimulated MAP2 kinase|MAP kinase isoform p44 (p44-MAPK)|Microtubule-associated protein 2 kinase|p44-ERK1|MAPK3|ERK1|PRKM3

Background: ERK1 and ERK2 belongs to the protein kinase superfamily. It is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. ERK1/2 catalized the reaction: ATP + a protein = ADP + a phosphoprotein. It is activated by tyrosine phosphorylation in response to insulin and NGF.

Poids moléculaire: 38-44 kDa

ID gène: 5595

UniProt: P27361

Pathways: Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins