MSH3 anticorps
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- Antigène Voir toutes MSH3 Anticorps
- MSH3 (MutS Homolog 3 (MSH3))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MSH3 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Immunogen affinity purified
- Pureté
- ≥95 % as determined by SDS-PAGE
- Immunogène
- mutS homolog 3
- Isotype
- IgG
- Top Product
- Discover our top product MSH3 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Date de péremption
- 12 months
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- Antigène
- MSH3 (MutS Homolog 3 (MSH3))
- Autre désignation
- MSH3 (MSH3 Produits)
- Synonymes
- anticorps ATMSH3, anticorps M7J2.90, anticorps M7J2_90, anticorps homolog of DNA mismatch repair protein MSH3, anticorps DUP, anticorps MRP1, anticorps D13Em1, anticorps Rep-3, anticorps Rep3, anticorps mutS homolog 3, anticorps DNA mismatch repair protein MSH3, anticorps homolog of DNA mismatch repair protein MSH3, anticorps mismatch repair protein, anticorps MSH3, anticorps Msh3
- Sujet
- Synonyms:DUC1, DUG Background:Component of the post-replicative DNA mismatch repair system(MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops(IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
- Poids moléculaire
- 123 kDa
- ID gène
- 4437
- UniProt
- P20585
- Pathways
- Réparation de l'ADN, Production of Molecular Mediator of Immune Response
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