anticorps vlcs, anticorps fatp2, anticorps vlacs, anticorps acsvl1, anticorps facvl1, anticorps im:7139614, anticorps slc27a2, anticorps wu:fb99g05, anticorps zgc:112376, anticorps ACSVL1, anticorps FACVL1, anticorps HsT17226, anticorps hFACVL1, anticorps FATP2, anticorps VLCS, anticorps Vlac, anticorps Vlacs, anticorps VLACS, anticorps solute carrier family 27 (fatty acid transporter), member 2 L homeolog, anticorps solute carrier family 27 member 2, anticorps solute carrier family 27 (fatty acid transporter), member 2a, anticorps solute carrier family 27 (fatty acid transporter), member 2, anticorps slc27a2.L, anticorps SLC27A2, anticorps slc27a2a, anticorps slc27a2, anticorps Slc27a2
Sujet
Synonyms:ACSVL1, FACVL1, FATP2, VLACS Background:The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.