TRPV6 anticorps

N° du produit ABIN7120140

Détail du produit anti-TRPV6 anticorps

Antigène: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRPV6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: transient receptor potential cation channel, subfamily V, member 6

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IP: 1:200-1:1000, IF: 1:10-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur TRPV6

Antigène: TRPV6 (Transient Receptor Potential Cation Channel, Subfamily V, Member 6 (TRPV6))

Autre désignation: TRPV6 (TRPV6 Produits)

Synonymes: anticorps ecac, anticorps trpv5-6, anticorps TRPV6, anticorps trpv6, anticorps CaT, anticorps ECaC, anticorps ABP/ZF, anticorps CAT1, anticorps CATL, anticorps ECAC2, anticorps HSA277909, anticorps LP6728, anticorps ZFAB, anticorps CAT, anticorps CaT1, anticorps Cac, anticorps Ecac2, anticorps Otrpc3, anticorps transient receptor potential cation channel, subfamily V, member 6, anticorps transient receptor potential cation channel subfamily V member 6, anticorps trpv6, anticorps TRPV6, anticorps Trpv6

Sujet: Synonyms:ABP/ZF, Calcium transport protein 1, CaT L, CaT like, CAT1, CATL, ECAC2, Epithelial calcium channel 2, HSA277909, LP6728, TRPV6, ZFAB Background:Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine(PubMed:11097838, PubMed:11278579, PubMed:11248124 PubMed:15184369, PubMed:23612980). Important for normal Ca(2+) ion homeostasis in the body, including bone and skin(By similarity). The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification(PubMed:15184369). Inactivation includes both a rapid Ca(2+)-dependent and a slower Ca(2+)-calmodulin-dependent mechanism, the latter may be regulated by phosphorylation. In vitro, is slowly inhibited by Mg(2+) in a voltage-independent manner. Heteromeric assembly with TRPV5 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.

Poids moléculaire: 82 kDa,70 kDa

ID gène: 55503

UniProt: Q9H1D0

Pathways: TCR Signaling