ZFP36L2 anticorps

N° du produit ABIN7120985

Détail du produit anti-ZFP36L2 anticorps

Antigène: ZFP36L2 (Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZFP36L2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: zinc finger protein 36, C3H type-like 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur ZFP36L2

Antigène: ZFP36L2 (Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))

Autre désignation: ZFP36L2 (ZFP36L2 Produits)

Synonymes: anticorps BRF2, anticorps ERF-2, anticorps ERF2, anticorps RNF162C, anticorps TIS11D, anticorps Brf2, anticorps Tis11d, anticorps fi22c11, anticorps wu:fi22c11, anticorps zgc:76924, anticorps ZFP36L2, anticorps XC3H-3, anticorps XC3H-3b, anticorps c3h-3, anticorps zfp36l2, anticorps brf2, anticorps erf-2, anticorps erf2, anticorps rnf162c, anticorps tis11d, anticorps cb198, anticorps cb480, anticorps fk89d11, anticorps id:ibd1247, anticorps sb:cb198, anticorps sb:cb480, anticorps wu:fb80h11, anticorps wu:fb92f07, anticorps wu:fk89d11, anticorps zfp36l1, anticorps zgc:153979, anticorps XC3H-2, anticorps berg36, anticorps brf1, anticorps c3h-2, anticorps cmg1, anticorps erf-1, anticorps erf1, anticorps rnf162b, anticorps tis11b, anticorps zfp36l1-a, anticorps zfp36l1-b, anticorps ZFP36 ring finger protein like 2, anticorps zinc finger protein 36, C3H type-like 2, anticorps ZFP36 ring finger protein-like 2 S homeolog, anticorps ZFP36 ring finger protein-like 2 L homeolog, anticorps ZFP36 ring finger protein-like 2, anticorps zinc finger protein 36, C3H type-like 1a, anticorps ZFP36 ring finger protein-like 1 L homeolog, anticorps ZFP36L2, anticorps Zfp36l2, anticorps zfp36l2, anticorps zfp36l2.S, anticorps zfp36l2.L, anticorps zfp36l1a, anticorps zfp36l1.L

Sujet: Synonyms:BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2 Background:mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity).

Poids moléculaire: 51 kDa

ID gène: 678

UniProt: P47974

Pathways: Stem Cell Maintenance