Recombinant BAK1 anticorps
Aperçu rapide pour Recombinant BAK1 anticorps (ABIN7127362)
Antigène
Voir toutes BAK1 AnticorpsType d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- BAK1 Recombinant Monoclonal Antibody
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human BAK1
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Isotype
- IgG
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Indications d'application
- WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
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Autre désignation
- BAK1
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Sujet
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Background: Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
Aliases: Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like protein 7, Bcl2-L-7, BAK1, BAK, BCL2L7, CDN1
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UniProt
- Q16611
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Pathways
- Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Antigène
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