Girdin anticorps (pSer417)

N° du produit ABIN7138609

Détail du produit anti-Girdin anticorps

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Épitope: pSer417

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Girdin est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of Serine 417(L-E-M(p)-A-Q) derived from Human Girdin .

Isotype: IgG

Information d'application

Indications d'application: IHC:1:50-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Girdin

Antigène: Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))

Autre désignation: CCDC88A (CCDC88A Produits)

Synonymes: anticorps APE, anticorps GIRDIN, anticorps GIV, anticorps GRDN, anticorps HkRP1, anticorps KIAA1212, anticorps A430106J12Rik, anticorps AI848406, anticorps Ape, anticorps C130096N06Rik, anticorps C330012F17Rik, anticorps D130005J21Rik, anticorps Girdin, anticorps Giv, anticorps Grdn, anticorps Hkrp1, anticorps DKFZp459N1815, anticorps RGD1306694, anticorps coiled-coil domain containing 88A, anticorps coiled coil domain containing 88A, anticorps CCDC88A, anticorps Ccdc88a

Sujet:

Background:

girdin IS a ubiquitously expressed actin binding protein that plays an important role in the formation of stress fibers and lamellipodia. Subsequent to phosphorylation by Akt, Girdin accumulates at the leading edge of migrating cells and appears to be crucial for the integrity of the actin cytoskeleton and for cell migration.

Enomoto A., Dev. Cell 9:389-402(2005).
Simpson F., Traffic 6:442-458(2005).
Hillier L.W., Nature 434:724-731(2005).

Aliases: AKT iphosphorylation enhancer antibody, Akt phosphorylation enhancer antibody, APE antibody, Ccdc88a antibody, Coiled coil domain containing 88A antibody, Coiled coil domain containing protein 88A antibody, Coiled-coil domain-containing protein 88A antibody, FLJ10392 antibody, G alpha interacting vesicle associated protein antibody, G alpha-interacting vesicle-associated protein antibody, Galpha interacting vesicle associated protein antibody, Girders of actin filament antibody, Girdin antibody, GIV antibody, GRDN antibody, GRDN_HUMAN antibody, HkRP1 antibody, Hook related protein 1 antibody, Hook-related protein 1 antibody, KIAA1212 antibody

UniProt: Q3V6T2