MAGED1 anticorps
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- Antigène Voir toutes MAGED1 Anticorps
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
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Reactivité
- Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAGED1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Souris, Rat
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- Peptide with sequence C-EAEARAEARNRMGIGDE derived from Mouse Melanoma-associated antigen D1.
- Isotype
- IgG
- Top Product
- Discover our top product MAGED1 Anticorps primaire
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- Indications d'application
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- MAGED1 (Melanoma Antigen Family D, 1 (MAGED1))
- Autre désignation
- Maged1 (MAGED1 Produits)
- Synonymes
- anticorps MAGED1, anticorps DLXIN-1, anticorps NRAGE, anticorps 2810433C11Rik, anticorps 5430405L04Rik, anticorps DXBwg1492e, anticorps Dlixin, anticorps Dlxin-1, anticorps Dlxin1, anticorps MAGE-D1, anticorps mFLJ00163, anticorps Nrage, anticorps MAGE family member D1, anticorps melanoma antigen family D, 1, anticorps melanoma antigen, family D, 1, anticorps MAGED1, anticorps Maged1
- Sujet
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Background: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression, and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53 phosphorylation and accumulation.
Zhao Z,et al.(2002) Sci China C Life Sci.45(4):412-20.
Shen WG,et al.(2007) Cell Commun Adhes.14(1):21-31.
Cheresh DA,et al. (1984) J Biol Chem.259(12):7453-9.Aliases: Maged1 antibody, Nrage antibody, Melanoma-associated antigen D1 antibody, Dlxin-1 antibody, MAGE-D1 antigen antibody, Neurotrophin receptor-interacting MAGE homolog antibody
- UniProt
- Q9QYH6
- Pathways
- Neurotrophin Signaling Pathway
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