Serotonin Receptor 2B anticorps (AA 382-481)

N° du produit ABIN7142626

Cet anticorps anti-Serotonin Receptor 2B est un anticorps Lapin Polyclonal détectant Serotonin Receptor 2B dans ELISA et IHC. Adapté pour Humain.

Aperçu rapide pour Serotonin Receptor 2B anticorps (AA 382-481) (ABIN7142626)

Antigène: Serotonin Receptor 2B (HTR2B)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Serotonin Receptor 2B est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Serotonin Receptor 2B anticorps

Épitope: AA 382-481

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human 5-hydroxytryptamine receptor 2B protein (382-481AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Serotonin Receptor 2B

Antigène: Serotonin Receptor 2B (HTR2B)

Autre désignation: HTR2B

Sujet:

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine.

Aliases: 5 HT 2B antibody, 5 HT 2B receptor antibody, 5 HT(2B) antibody, 5 HT2B antibody, 5 hydroxytryptamine (serotonin) receptor 2B antibody, 5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody, 5 hydroxytryptamine 2B receptor antibody, 5 hydroxytryptamine receptor 2B antibody, 5-HT-2B antibody, 5-HT2B antibody, 5-hydroxytryptamine receptor 2B antibody, 5HT(2B) antibody, 5HT2B Receptor antibody, 5HT2B_HUMAN antibody, 5HT2F antibody, Htr 2b antibody, Htr2b antibody, NP75 protein antibody, SEROTONIN 5HT2B RECEPTOR antibody, Serotonin receptor 2B antibody, Stomach fundus serotonin receptor antibody

UniProt: P41595

Pathways: Signalistation JAK/STAT, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process