ARPC3 anticorps (AA 2-175)

N° du produit ABIN7143089

Détail du produit anti-ARPC3 anticorps

Antigène: ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))

Épitope: AA 2-175

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARPC3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Actin-related protein 2/3 complex subunit 3 protein (2-175AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARPC3

Antigène: ARPC3 (Actin Related Protein 2/3 Complex, Subunit 3, 21kDa (ARPC3))

Autre désignation: ARPC3 (ARPC3 Produits)

Synonymes: anticorps ARC21, anticorps p21-Arc, anticorps 1110006A04Rik, anticorps 21kDa, anticorps AA408672, anticorps AI788639, anticorps p21-Ar, anticorps p21Arc, anticorps arc21, anticorps p21-arc, anticorps zgc:86828, anticorps actin related protein 2/3 complex subunit 3, anticorps actin related protein 2/3 complex, subunit 3, anticorps actin related protein 2/3 complex subunit 3 L homeolog, anticorps actin related protein 2/3 complex, subunit 3, 21kDa, anticorps actin related protein 2/3 complex subunit 3 pseudogene, anticorps actin-related protein 2/3 complex subunit 3, anticorps actin-related protein 2/3 complex subunit 3 pseudogene, anticorps ARPC3, anticorps Arpc3, anticorps arpc3.L, anticorps LOC738738, anticorps arpc3, anticorps LOC100036831, anticorps LOC100341254

Sujet:

Background: Component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079). In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA (PubMed:29925947). The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs) (PubMed:29925947).

Aliases: ARPC3 antibody, ARC21Actin-related protein 2/3 complex subunit 3 antibody, Arp2/3 complex 21 kDa subunit antibody, p21-ARC antibody

UniProt: O15145

Pathways: Signalisation RTK, Regulation of Actin Filament Polymerization